Medical guides

Positive ANA: what does my result mean?

A positive antinuclear antibody result can be worrying, but on its own it is not a diagnosis. Its meaning depends on why the test was requested and the clinical picture.

What are ANA?

Autoantibodies directed against components of the cell nucleus. They may be found in autoimmune diseases but also in healthy people, particularly at low titres and with age.

What is assessed?

Titre, pattern, specific antibodies and, above all, whether compatible symptoms or signs are present.

When to seek advice

When a positive ANA comes with arthritis, Raynaud's phenomenon, skin lesions, persistent dryness or other abnormal tests.

Related content

A hot, very painful and swollen joint, especially with fever, requires urgent medical attention.